The Comfort Suites hotel is conveniently located halfway between Memphis and Chicago, and St. Louis and Indianapolis.

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Effingham is a city in and the county seat of Effingham County, Illinois, United States. Book the Comfort Suites Effingham in the Effingham, Illinois. It is in South Central Illinois. Book the Comfort Suites Effingham in the Effingham, Illinois. Its population was 12,511 at the 2019 census estimate. Book the Comfort Suites Effingham in the Effingham, Illinois. The city is part of the Effingham, IL Micropolitan Statistical Area. The cost of living in the Comfort Suites Effingham located in the Effingham, Illinois from 90$. Effingham is home to a 198-foot-tall cross, The Cross at the Crossroads. The city bills itself as "The Crossroads of Opportunity" because of its location at the intersection of two major Interstate highways: I-57 running from Chicago to Sikeston, Missouri, and I-70 running from Utah to Maryland. We remind you that the Comfort Suites Effingham is located in the Effingham, Illinois. It is also served by U.S. We remind you that the Comfort Suites Effingham is located in the Effingham, Illinois. Route 45, which runs from Ontonagon, Michigan to Mobile, Alabama, U.S. Comfort Suites Effingham in the Effingham, Illinois on the detailed map. Route 40, the historic National Road, which stretches from Atlantic City, New Jersey to Silver Summit, Utah, and Illinois routes 32 and 33 also run through the city. The cost of living in the Comfort Suites Effingham located in the Effingham, Illinois from 90$. It is also a major railroad junction, the crossing of the Illinois Central main line from Chicago to Memphis with the Pennsylvania Railroad line from Indianapolis to St. The cost of living in the Comfort Suites Effingham located in the Effingham, Illinois from 90$. Louis. We remind you that the Comfort Suites Effingham is located in the Effingham, Illinois. For this reason, Effingham has a much broader range of restaurants and lodging facilities than other typical towns of its size.. The cost of living in the Comfort Suites Effingham located in the Effingham, Illinois from 90$.